Superantigen-Induced Steroid Resistance Depends on Activation of Phospholipase Cβ2
نویسندگان
چکیده
منابع مشابه
A dynamic model of membrane-bound phospholipase Cβ2 activation by Gβγ subunits.
Phospholipase C (PLC) β2, a well studied member of the family of enzymes that catalyze the hydrolysis of the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP₂) into secondary messengers, can be activated by the Gβγ subunits of heterotrimeric G-proteins in a manner that depends on the presence and composition of the associated phospholipid membrane surface. The N-terminal pleckstrin hom...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2013
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1202898